Assessment of liver fat in an obese patient population using noncontrast CT fat percent index

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MRI Quantification of Liver Fat in an Obese Population

T. Tuthill, D. Raunig, A. Hickman, B. Peterson, B. Wyman VirtualScopics, Groton, CT, United States, Pfizer, Groton, CT, United States Introduction An elevation in liver fat content (hepatic steatosis) is a common but poorly understood aspect of liver disease and drug toxicity. Investigations into the mechanisms of hepatic steatosis are hampered by the lack of a reliable and non-invasive measure...

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Hepatic steatosis: correlations of body mass index, CT fat measurements, and liver density with biopsy results.

PURPOSE To assess the relationship between body mass index (BMI), subcutaneous and intra-abdominal fat, liver density, and histopathologic hepatic steatosis. MATERIALS AND METHODS In this retrospective study, 143 patients (male/female, 67/76; mean age, 50 years) underwent a non-targeted transjugular (n = 125) or percutaneous (n = 18) liver biopsy between 2006 and 2010. The biopsy indications ...

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Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?

Liver fat represents a balance between input, secretion, and oxidation of fatty acids. As humans spend the majority of a 24-h period in a postprandial state, dietary fatty acids make an important contribution to liver fat metabolism. We compared hepatic fatty acid partitioning in healthy lean (n = 9) and abdominally obese (n = 10) males over 24 h. Volunteers received three mixed meals adjusted ...

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BACKGROUND Obesity is a serious disease that is associated with an increased risk of diabetes, hypertension, heart disease, stroke, and cancer, among other diseases. The United States Centers for Disease Control and Prevention (CDC) estimates a 20% obesity rate in the 50 states, with 12 states having rates of over 30%. Currently, the body mass index (BMI) is most commonly used to determine adip...

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ژورنال

عنوان ژورنال: Clinical Imaging

سال: 2014

ISSN: 0899-7071

DOI: 10.1016/j.clinimag.2014.01.005